Reply to: "Letter to the editor: Comparing pace and speed in the pulmonary circulation?".
نویسندگان
چکیده
which does result in wave speed in m/s. However, the correct equation was used in processing of the data in the article (Fig. 1A). In fact, if we had calculated “pace,” a significant bias would be seen, as shown in Fig. 1B. Weir-McCall rightly draws attention to the difficulty of measuring pulse wave velocity (PWV) in the pulmonary circulation and the relatively wide limits of agreement between the two methods described in the appendix of this study. Unfortunately, there is no noninvasive reference standard method of assessing PWV in the pulmonary circulation. We compared our “three-point Q/A method” of assessing PWV with an alternative energy minimization technique to exclude large biases. The minimal bias suggests that there is no systematic difference between these two techniques. However, the energy minimization technique was developed for the coronary circulation, where it is not possible to calculate the PWV using the Q/A method. We believe that in the pulmonary circulation the Q/A method is more valid, which may account for the relatively wide limits of agreement. However, we agree that more work is required in validating these metrics and one possibility is through the use of in silico models.
منابع مشابه
Comment to the Letter to the Editor: Subjective Symptoms Related to GSM Radiation from Mobile Phone Base Stations: a cross-sectional study In reply to the comments by Seyed Mohammad Javad Mortazavi
متن کامل
Environmental gamma radiation: a comment (Letter to the Editor)
Editor, I read the recent publication by Toossi et al. with a great interest (1). Toossi et al. concluded that “Average gonad and bone marrow doses for North Khorasan, Boshehr and Hormozgan provinces were less than the corresponding values for normal area (2).” There are some facts on this report to be concerned. I agree that the detected levels might be high in the mentioned area, but th...
متن کاملLetter to editor " Applying High-quality DNA Melting Curve Analysis in Identifying Staphylococcus aureus and Methicillin-resistant Strains "
Letter to editor " Applying High-quality DNA Melting Curve Analysis in Identifying Staphylococcus aureus and Methicillin-resistant Strains " Ramezan Ali Ataee Professor, Department of Medical Microbiology, Faculty of Medicine, Hospital Research Development Committee, Applied Microbiology Research Center, System Biology, Poisoning Institute, Baqiyatallah University of Medical Sciences, T...
متن کاملDear Editor,
I read with interest Dr. Yazdani's reply about the article entitled “administration of magnesium sulfate to women with premature labor: The effect on bleeding time”.1 In my review of hematology references, I could not find any reference for determining hemoglobin (Hb) sooner than 24 hrs and Dr. Yazdani had not cited any reference either. However, about the influence of Hb on homeostasis, ther...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- American journal of physiology. Heart and circulatory physiology
دوره 310 7 شماره
صفحات -
تاریخ انتشار 2016